Adhesion in Leukocyte Homing and Differentiation by F. Melchers (auth.), Dominique Dunon Ph.D., Charles R.

By F. Melchers (auth.), Dominique Dunon Ph.D., Charles R. Mackay Ph.D., Beat A. Imhof Ph.D. (eds.)

This quantity of present issues in Microbiology and Immunology used to be deliberate in parallel with an EM BO workshop on cell-cell Interactions in Leukocyte Homing and Differentiation held on the Basel Institute for Immunology in November 1992, and plenty of of the workshop audio system have contributed to it. phone adhesion is among the such a lot dynamic fields of organic learn and awarded during this booklet is the present wisdom at the constitution and serve as of the most important households of cellphone adhesion molecules-the integrins, the selectins, the immunoglobulin superfamily, and CD44. advanced interactions among the participants of those households mediate diversified adhesion capabilities, together with leukocyte-leukocyte interactions, lymphocyte homing, irritation, and lymphocyte-stromal telephone interplay in the course of hematopoiesis. loads of emphasis is put on the regulatory components that keep watch over the expression and serve as of adhesion molecules. Cytokines not just result in the expression of sure adhesion molecules, yet can also regulate their practical prestige. for example, the integrins exist in both an inactive nonfunctional shape or an lively sensible shape, and a couple of intracellular or extracellular stimuli adjust integrin functionality. this is often rather very important in the course of leukocyte binding to endothelium and transendothelial migration, which proceeds via a cascade of adhesion occasions. even though cellphone adhesion molecules play a tremendous function in lots of procedures, this publication concentrates on their function in the immune method. a couple of chapters speak about the migration of lymphocytes among hematopoietic organs comparable to the thymus, lymph nodes, Peyer's patches, and spleen.

Show description

Read Online or Download Adhesion in Leukocyte Homing and Differentiation PDF

Best nonfiction_8 books

Parallel Processing for Jet Engine Control

Parallel Processing functions for Jet Engine keep an eye on is a quantity within the new Advances in commercial regulate sequence, edited by way of Professor M. J. Grimble and Dr. M. A. Johnson of the economic keep an eye on Unit, collage of Strathclyde. The booklet describes the mapping and cargo balancing of fuel turbine engine and controller simulations onto arrays of transputers.

Variational Methods for Discontinuous Structures: Applications to image segmentation, continuum mechanics, homogenization Villa Olmo, Como, 8–10 September 1994

In recent times many researchers in fabric technology have concentrated their realization at the research of composite fabrics, equilibrium of crystals and crack distribution in continua topic to so much. while a number of new concerns in computing device imaginative and prescient and photo processing were studied extensive. the certainty of a lot of those difficulties has made major growth because of new tools constructed in calculus of diversifications, geometric degree thought and partial differential equations.

Coping with Financial Fragility and Systemic Risk

Dealing with monetary Fragility and Systemic threat identifies and discusses the resources of perceived fragility in monetary associations and markets and its power results in the course of the economic system. It then examines deepest quarter ideas for facing systemic probability and mitigating the implications.

Forest site and productivity

A data of wooded area web site and wooded area productiveness variables is prime to sound wooded area perform far and wide. the facility to spot websites and placement difficulties safely and control productiveness variables for upkeep or development of productiveness is the foundation of recent woodland administration. even supposing the fundamental proof concerning wooded area web site and productiveness observe through the global, the appliance of data and the reaction to manipulation fluctuate significantly and rely on neighborhood woodland stipulations.

Additional resources for Adhesion in Leukocyte Homing and Differentiation

Sample text

Pierschbacher MD, Herzig, MA, Mujoo K (1986) Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. J Cell Bioi 102: 688-696 Cheresh DA. Pytela R, Pierschbacher MD, Klier FG, Ruoslahti E, Reisfeld RA (1987) An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in a divalent cation-dependent functional complex with the disialoganglioside GD2. J Cell Bioi 105: 1163-1173 Cheresh DA. Smith JW, Cooper HM, Quaranta V (1989) A novel vitronectin receptor integrin (IXvPx) is responsible for distinct adhesive properties of carcinoma cells.

Nature 320: 531-533 Humphrins MJ, Akiyama SK, Komoriya A, Olden K, Yamada KM (1986) Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion. J Cell Bioi 103: 2637-2647 Humphries MJ, Komoriya A. Akiyama SK, Olden K, Yamada KM (1987) Neurite extension of Integrins and Their Ligands 29 chicken peripheral nervous system neurons on fibronectin: relative importance of specific adhesion sites in the central cell-binding domain and the alternatively spliced type III connecting segment.

J Immunol144: 777-784 Bodary SC, McLean JW (1990) The integrin /31 subunit associates with the vitronectin receptor IXv subunit to form a novel vitronectin receptor in a human embryonic kidney cell line. J Bioi Chem 265: 5938-5941 Bogaert T, Brown N, Wilcox M (1987) The drosophilia PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments. Cell 51: 929-940 Bossy B, Bossy-Wetzel E, Reichardt LF (1991) Characterization of the integrin IXs subunit: a new integrin /3,-associated subunit, which is prominently expressed on axons and on cells in contact with basal laminal in chick embryos.

Download PDF sample

Rated 4.63 of 5 – based on 43 votes