Atlas of Soft Tissue and Bone Pathology: With Histologic, by Leslie G. Dodd MD, Marilyn M. Bui MD PhD

By Leslie G. Dodd MD, Marilyn M. Bui MD PhD


This is an abundantly illustrated source for prognosis of bone and delicate tissue lesionsóa specific problem as a result of their rarity and complexity. as well as conscientiously chosen histologic pictures, this certain atlas complements commonplace visible details with illustrations of imaging findings, cytology, and molecular and cytogenetic details. This vibrant pictorial survey is prepared in a pattern-oriented process in keeping with the particular operating technique utilized in day-by-day practice.

The authors are specialist educators in surgical and cytopathology and skilled diagnosticians within the complexities of soppy tissue and bone pathology. This richly illustrated and concise reference might be a pragmatic and indispensible device for common pathologists and pathologists in education, who're required to diagnose bone and delicate tissue pathologies. it's also a superb source for physicians looking a brief survey of sarcoma.

Key Features:

  • Offers a realistic, pattern-oriented diagnostic technique that mirrors the operating technique utilized in day-by-day practice
  • Augments histologic pictures with illustrations of imaging findings, cytology, and molecular and cytogenetic information
  • Authored via well-known professional diagnosticians and academics within the field


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Additional resources for Atlas of Soft Tissue and Bone Pathology: With Histologic, Cytologic, and Radiologic Correlations

Sample text

6 Aspirates of pleomorphic lipoma may have large nuclei and multinucleate cells. 3 Hibernoma H ibernoma is an unusual benign neoplasm that is thought to be a morpohologic variant of a benign lipoma. It is composed of so-called “brown fat,” which is normally identified in newborns and hibernating animals. In infants, about 5% of body fat is of the “brown” variety. It is normally distributed along the upper back region and is thought to provide a survival advantage for infants who are susceptible to cold.

After radiographic evaluation, cross-sectional imaging, such as CT or MRI, is often performed in the initial diagnostic evaluation of bony and soft tissue neoplasms. CT and MRI demonstrate numerous separate and complementary findings, which help characterize musculoskeletal tumors. CT better demonstrates tumor mineralization, cortical involvement, and visualization of fractures, while being extremely useful in patient staging when necessary. MRI has improved soft tissue contrast compared to CT, allowing for differentiation of various soft tissue elements within a tumor (ie, chondroid, myxoid, or fibrous elements), which correlate with findings at gross tumor dissection and final tumor pathology.

5 This ALT has numerous spindled nuclei with rare large and irregular forms. 6 The “sclerosing” subtype of ALT or welldifferentiated liposarcoma (WDL) with abundant stroma and minimal nuclear pleomorphism. 7 Careful examination of a sclerosing variant of ALT/WDL shows rare hyperchromatic and atypical nuclei. 8 Small floret-like cells are frequently identified in ALT/WDL. They are not unique to this neoplasm as they are often identified in the pleomorphic variant of lipoma. 9 A classic lipoblast with a single large vacuole in a signet ring form.

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